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Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function
Barwell, James.  Biochimica et Biophysica Acta - Molecular Cell Research.  v. Vol.1813. no. No.10.   2011-10. p. 1906 - 1916... issn: 0167-4889 .   

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