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Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement : a randomized controlled trial (TRANX-K)
Alshryda, Sattar.  The Journal of Bone and Joint Surgery.  v. 95. no. 21.   2013-11. p. 1961 - 1968... issn: 0021-9355 .   

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